Structural and Enzymatic Aspects of Rhodopsin Phosphorylation

نویسندگان
چکیده

منابع مشابه

Rhodopsin phosphorylation: 30 years later.

Phototransduction in vertebrate photoreceptor cells mediated by rhodopsin is one of the most comprehensively examined G protein-coupled receptor (GPCR) signaling pathways. The signal transduction pathway can be mapped from the initial absorption of light to conformational changes within rhodopsin, through activation of the G protein transducin, and to the ultimate closure of the cation cGMP-gat...

متن کامل

Enzymatic phosphorylation of butyrate.

Conservation of thiol ester bond energy through a reaction sequence involving phosphorolysis of acetyl coenzyme A by phosphotransacetylase (1, 2) and the subsequent formation of adenosine triphosphate from adenosine diphosphate and acetyl phosphate by acetokinase (3, 4) is well established in fermentative bacteria. A similar reaction sequence involving butyryl coenzyme A, phosphotransbutyrylase...

متن کامل

Enzymatic phosphorylation of acetate.

The metabolic utilization of acetate (oxidation via the citric acid cycle, synthesis of higher fatty acids, cholesterol, and possibly other compounds) requires a preliminary activation through conversion to acetyl C0A.l Two main mechanisms are known to bring about this activation (2). One of these mechanisms, utilized by animal tissues, yeast, and some bacteria, seems to involve a single enzyme...

متن کامل

Functional and structural characterization of rhodopsin oligomers.

A major question in G protein-coupled receptor signaling concerns the quaternary structure required for signal transduction. Do these transmembrane receptors function as monomers, dimers, or larger oligomers? We have investigated the oligomeric state of the model G protein-coupled receptor rhodopsin (Rho), which absorbs light and initiates a phototransduction-signaling cascade that forms the ba...

متن کامل

Enzymatic phosphorylation of macrolide antibiotics.

Five macrolide antibiotics (erythromycin A, 1; oleandomycin, 3a; tylosin, 4a; spiramycins, 5a; leucomycin A3, 6a) have been phosphorylated enzymatically using cell-free extracts derived from Streptomyces coelicolor UC 5240. The necessary cofactors and the rates of the conversion have been determined.

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 1996

ISSN: 0021-9258

DOI: 10.1074/jbc.271.9.5215